Parker Lab

Unraveling the neural circuits of visual perception and behavior through cutting-edge techniques.

Our Focus

What We Do

We aim to understand natural visual behaviors and their underlying neural circuits. We employ a variety of techniques including ethological behavioral paradigms, large-scale electrophysiology, and two-photon calcium imaging in freely moving animals.

Neural Circuits

Mapping the intricate pathways that govern visual perception.

Advanced Imaging

Using two-photon calcium imaging to observe neural activity in real-time.

Behavioral Studies

Analyzing natural behaviors in freely moving subjects to understand brain function.

Our Discoveries

Showcasing Our Experiments

Explore a selection of our key experiments, featuring GIFs of our research in action.

Distance Estimation Jumping Experiments

Video tracking of mice jumping with neural recordings.

Freely Moving Mice Behavior

Video tracking of mice navigating a complex maze, correlated with neural recordings.

Freely Moving Mice with Head-Mounted IMU

Mice POV of their environment, correlated with neural recordings, and head-mounted IMU data.

Our Work

Key Publications

Neural coding and circuitry of active vision in mice

PRL Parker

Journal of Vision 25 (9), 1604-1604 (2025)

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Building egocentric models of local space from retinal input

DM Martins, JM Manda, MJ Goard, PRL Parker

Current Biology 34 (23), R1185-R1202 (2024)

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A dynamic sequence of visual processing initiated by gaze shifts

PRL Parker, DM Martins, ESP Leonard, NM Casey, SL Sharp, ETT Abe, ...

Nature Neuroscience 26 (12), 2192-2202 (2023)

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Joint coding of visual input and eye/head position in V1 of freely moving mice

PRL Parker, ETT Abe, ESP Leonard, DM Martins, CM Niell

Neuron 110 (23), 3897-3906. e5 (2022)

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Distance estimation from monocular cues in an ethological visuomotor task

PRL Parker, ETT Abe, NT Beatie, ESP Leonard, DM Martins, SL Sharp, ...

eLife 11, e74708 (2022)

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Precise levels of nectin-3 are required for proper synapse formation in postnatal visual cortex

J Tomorsky, PRL Parker, CQ Doe, CM Niell

Neural Development 15, 1-20 (2020)

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Movement-related signals in sensory areas: Roles in natural behavior

PRL Parker, MA Brown, MC Smear, CM Niell

Trends in neurosciences 43 (8), 581-595 (2020)

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A Hallucinogenic Serotonin-2A Receptor Agonist Reduces Visual Response Gain and Alters Temporal Dynamics in Mouse V1

AM Michaiel, PRL Parker, CM Niell

Cell Reports 26 (13), 3475-3483. e4 (2019)

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Our Supporters

Funding & Sponsors

Whitehall FoundationRutgers University